產(chǎn)品名稱 CPI-613 from BIOVISION, INC.
產(chǎn)品貨號(hào) 9464-50
產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià)，電話：010-67529703
產(chǎn)品規(guī)格 50 mg
產(chǎn)品品牌 BIOVISION, INC.
產(chǎn)品概述
產(chǎn)品詳情
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Product NameCPI-613
DescriptionCPI-613 is a non-redox active lipoate derivative that acts as a selective inhibitor mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase. In vitro, CPI-613 dose-dependently and efficiently kills H460 human lung cancer cells and Saos-2 human sarcoma cells. In vitro, CPI-613 treatment potently disrupts H460 cancer cell mitochondrial metabolism including inhibition of PDH complex activity. CPI-613 treatment also leads to loss of mitochondrial membrane potential as assessed by JC-1 mitochondrial uptake. CPI-613 also induces apoptotic and non-apoptotic cell death in the cells of H460 human lung cancer and Saos-2 human sarcoma in vitro. MW: 388.59. Purity ≥98% by HPLC
Size50 mg
Concentrationn/a
Applicationsn/a
Other Names6,8-Bis[(phenylmethyl)thio]octanoic acid
Gene, Accession, CAS #CAS: 95809-78-2
Catalog #9464-50
Price
Order / More InfoCPI-613 from BIOVISION, INC.
Product Specific Referencesn/a
產(chǎn)品資料
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