| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | BioSim? anti-Trastuzumab (Herceptin?) (Human) ELISA Kit |
|---|
| Description | Trastuzumab (Herclon?, Herceptin?) is a recombinant DNA-derived humanized monoclonal antibody that selectively targets the extracellular domain of the human epidermal growth factor receptor 2 protein (HER2). Trastuzumab has antitumor activity against HER2-positive human breast tumor cells in laboratory models and is active for the treatment of women with HER2-overexpressing breast cancers. In HER2 overexpressing cells, trastuzumab markedly down-regulates HER2 expression by accelerating receptor endocytosis and degradation and inhibits cell cycle progression by inducing the formation of p27Kip1/Cdk2 complexes. However, some patients develop unwanted immunogenicity, which leads to production of anti-drug-antibodies (ADAs) inactivating |
|---|
| Size | 100 assays |
|---|
| Concentration | n/a |
|---|
| Applications | This ELISA kit is used for quantitative measurement of antibody against Trastuzumab in human serum and plasma |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | E4386-100 |
|---|
| Price | |
|---|
| Order / More Info | BioSim™ anti-Trastuzumab (Herceptin®) (Human) ELISA Kit from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|