| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD49e |
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| Clone | 5H10-27(MFR5) |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | purified, azide-free |
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| Size | 500 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), Block, Costim, IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LEAF? Purified anti-mouse CD49e. CD49e is a 135 kD protein, also known as α5 integrin or VLA-5 α chain. It is a member of the integrin family, expressed on thymocytes, splenic B cells, activated T cells, and mast cells. CD49e associates with CD29 (integrin β1 chain) to form the fibronectin receptor (VLA-5). CD49e plays a critical role in both adhesion and T cell costimulation. The primary ligand for CD49e/CD29 (VLA-5) is fibronectin. The 5H10-27(MFR5) antibody has been shown to block CD49e mediated interactions and promote the in vitro stimulation of CD8+ T cells. |
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| Immunogen | (C57BL/6 x A/J)F1 mouse mast cell line |
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| Other Names | α5 integrin, VLA-5 α chain, Integrin α5 |
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| Gene, Accession # | Gene ID: 16402 |
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| Catalog # | 103808 |
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| Price | |
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| Order / More Info | CD49e Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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