| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD51 |
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| Clone | P1F6 |
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| Host Species | Mouse |
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| Reactive Species | human, rat, cross-reactivity: hamster |
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| Isotype | IgG1, κ |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human/rat CD51 (Integrin αvβ5). CD51 is a type I integral membrane glycoprotein, known as vitronectin receptor α chain, or integrin αV. It forms heterodimer with integrin β1 (CD29), β3 (CD61), β5, β6, or β8. CD51 contains two disulfide-linked subunits of 125 kD and 24 kD, and is expressed on endothelial cells, fibroblasts, macrophages, platelets, osteoclasts, neuroblastoma, melanoma, and hepatoma cells. Many extracellular matrix proteins with RGD-motifs are CD51 ligands. In association with its β chains, CD51 binds vitronectin, von Willebrand factor, fibronectin, thrombospondin, osteopontin, fibrinogen, and laminin. CD51, as an adhesion molecule, plays important roles in leukocytes homing and rolling and mediates bone absorption and angiogenesis. |
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| Immunogen | The P1F6 monoclonal antibody was generated against human small cell lung carcinoma cells (UCLA P3). |
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| Other Names | ITGAV, MSK8, VNRA, VTNR |
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| Gene, Accession # | Gene ID: 3685 |
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| Catalog # | 920004 |
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| Price | |
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| Order / More Info | CD51 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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