| 產(chǎn)品詳情 |
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| Antigenic Specificity | Thymidine Phosphorylase (TYMP) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 200 μg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Thymidine phosphorylase (TP) is a platelet-derived endothelial cell growth factor (PD-ECGF) that catalyzes the formation of thymine and 2-deoxy-D-ribose-1-phosphate from thymidine and orthophosphate. This intracellular enzyme is capable of both promoting angiogenesis and inhibiting apoptosis. Thymidine phosphorylase catalytic activity is required for its angiogenic function. Increased expression of TP/PD-ECGF is seen in a wide variety of different solid tumors and inflammatory diseases and is often associated with poor prognosis. Alternatively, TP can activate fluorouracil derivative (DFUR) prodrugs and increase the antitumor activity of the related treatment. The use of thymidine phosphorylase as a cancer therapeutic target has been studied extensively, with emphasis on either inhibiting TP enzymatic activity or increasing enzyme induction with concomitant DFUR treatment.Synonyms: TYMP, ECGF1, MNGIE, PDECGF, TP, hPD-ECGF |
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| Immunogen | Recombinant protein of human TYMP |
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| Other Names | typh|CD363|CHEDG1|D1S3362|ECGF1|EDG-1|EDG1|S1P1|ECGF|MEDPS1|MNGIE|MTDPS1|PDECGF|TP|hPD-ECGF|Ecgf1|2900072D10Rik|PD-ECGF|Pdgfec |
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| Gene, Accession # | Gene ID: 1890,72962,315219 |
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| Catalog # | ABIN1514795 |
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| Price | |
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| Order / More Info | Thymidine Phosphorylase (TYMP) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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