| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | SU 11274 |
|---|
| Description | A specific, ATP-competitive small molecule inhibitor of the catalytic activity of Met. Displays selectivity for Met enzyme versus a panel of other tyrosine kinases with the following IC50 values: Met = 0.02 μM, Flk = 1.3 μM, EGFR = >100 μM, PDGFβR = >20 μM, Tie2 = >100 μM, c-src = >10 μM, cdk2 = >10 μM, and FGFR-1 = 9.7 μM). Inhibition of the Met kinase activity by SU11274 leads to time- and dose-dependent reduced cell growth and induced G1 cell cycle arrest and apoptosis. MW: 568.09. Purity ≥98% by HPLC |
|---|
| Size | 25 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 3Z)-N-(3-Chlorophenyl)-3-({3,5-dimethyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl}methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide |
|---|
| Gene, Accession, CAS # | CAS: 658084-23-2 |
|---|
| Catalog # | 1938-25 |
|---|
| Price | |
|---|
| Order / More Info | SU 11274 from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|