| 產(chǎn)品詳情 |
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| Antigenic Specificity | WAVE1 |
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| Clone | K91/36 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 μl |
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| Concentration | n/a |
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| Applications | Western Blot (WB), IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-WAVE1. Organ morphogenesis can occur through cellular response to extracellular signals that alter actin dynamics. Wiskott-Aldrich syndrome protein-family verprolin homologous protein 1 (WAVE1) is an actin-interacting protein involved in brain morphogenesis. WAVE1 interacts with Arp (actin-related proteins) 2/3 to regulate the cytoskeleton. WAVE proteins mediate lamellipodia formation and are critical for normal CNS myelination. WAVE1 can be phosphorylated by Cdk5 to downregulate Arp2/3 complex-dependent actin polymerization. |
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| Immunogen | This monoclonal antibody was raised against a synthetic peptide corresponding to amino acids 477-498 of human Wave1/Wasp family 1 protein. |
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| Other Names | Wiskott-Aldrich syndrome protein family member 1, protein WAVE-1, WASP family protein member 1, homology of dictyostelium scar 1, verprolin homology domain-containing protein 1, MMS-5208-100 |
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| Gene, Accession # | Gene ID: 8936 |
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| Catalog # | 817901 |
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| Price | |
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| Order / More Info | WAVE1 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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