| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD85d (ILT4) |
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| Clone | 42D1 |
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| Host Species | Rat |
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| Reactive Species | human |
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| Isotype | IgG2a, κ |
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| Format | PE-Dazzle? 594 conjugate |
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| Size | 25 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PE/Dazzle? 594 anti-human CD85d (ILT4). CD85 is a group of Ig superfamily tansmembrane glycoproteins called Ig-Like Transcripts (ILTs) or Leukocyte Immunoglobulin-like Receptors (LIRs). It is composed of both activating and inhibitory isoforms. The activating subset of ILTs is characterized by containing short cytoplasmic domains and positively charged arginine residues, while the inhibitory isoforms display long cytoplasmic tails containing ITIM motifs. CD85d is a 95kD inhibitory receptor, also known as ILT4, LIR2, or MIR10. ILT4 is expressed on the surface of monocytes/macrophages, and dendritic cells. ILT4 acts as an inhibitory receptor through recruitment of SHP-1 and SHP-2 protein tyrosine phosphatases. The ligands of ILT4 are HLA-A, -B and nonclassical MHC-I molecule HLA-G1. |
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| Immunogen | n/a |
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| Other Names | CD85, ILT4, MIR10, Leukocyte Immunoglobulin-Like Receptor subfamily B member 2 (LILRB2), Leukocyte Immunoglobulin-like Receptor 2 (LIR-2) |
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| Gene, Accession # | Gene ID: 10288 |
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| Catalog # | 338709 |
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| Price | |
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| Order / More Info | CD85d (ILT4) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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