| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD354 |
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| Clone | TREM-37 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b, κ |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), ELISA Capture, Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human CD354 (TREM-1). TREM-1 is a 30 kD glycoprotein also known as triggering receptor expressed on myeloid cells 1, and triggering receptor expressed on monocytes 1. It is a Type I membrane protein that contains an immunoglobulin-like V-type domain. Alternatively spliced protein variant may be secreted. TREM-1 is highly expressed on peripheral blood myeloid cells (particularly mature monocytes and granulocytes); TREM-1 expression can be further upregulated by bacteria, fungi and lipopolysaccharide. TREM-1 has been shown to interact with the adaptor protein DAP12 to stimulate neutrophil and monocyte-mediated inflammatory responses through the triggering and release of pro-inflammatory cytokines and chemokines. TREM-1 is thought to amplify inflammatory responses to fungal and bacterial infections and potentiate septic shock. This antibody has been shown to be useful for Western blotting, flow cytometric staining, and ELISA pairing with biotinylated TREM-26 antibody (Cat. No. 314904) as a detection antibody. |
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| Immunogen | Recombinant human TREM-1 |
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| Other Names | Triggering receptor expressed on myeloid cells 1, triggering receptor expressed on monocytes 1 |
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| Gene, Accession # | Gene ID: 54210 |
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| Catalog # | 316102 |
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| Price | |
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| Order / More Info | CD354 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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