| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | CD309 |
|---|
| Clone | A16085I |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG2b, κ |
|---|
| Format | Alexa Fluor? 594 conjugate |
|---|
| Size | 100 μg |
|---|
| Concentration | n/a |
|---|
| Applications | IHC-P |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Alexa Fluor? 594 anti-human CD309 (VEGFR2). CD309, also known as VEGF-R2, KDR, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, and VEGF-D splice isoforms. Activation of VEGF-R2 with its ligands results in the receptor dimerization and autophosphorylation, stimulating endothelial cell proliferation and migration. |
|---|
| Immunogen | Recombinant Human VEGFR2-Fc Chimera |
|---|
| Other Names | VEGFR2, KDR |
|---|
| Gene, Accession # | Gene ID: 3791 |
|---|
| Catalog # | 374004 |
|---|
| Price | |
|---|
| Order / More Info | CD309 Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|