| 產品詳情 |
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| Product Name | Caspase-3 Proform, mouse recombinant |
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| Description | Caspase-3 (also know as CPP32, Yama and apopain) is a member of the caspase family of cysteine proteases. Caspase-3 exists in cells as an inactive 32 kDa proenzyme. Proteolytic processing of this inactive proenzyme generates the 17 kD and 12 kD subunits which, when assembled as a tetramer (a pair of heterodimers), form the active caspase. Cascades of caspase activation have been shown to be key signal-transducing events in apoptosis. Procaspase-3, like other procaspases with short N-terminal prodomains, is considered to be a downstream or ``effector'' enzyme. Pro-caspase-3 can be cleaved and activated by caspase-8 and -10 which are themselves activated through interaction with death ligand receptor/adapter protein complexes (e.g., Fas/FADD). |
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| Size | 5 μg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Caspase-3, Short name=CASP-3, Apopain, Cysteine protease CPP32, Short name=CPP-32, FLICE, Protein Yama, SREBP cleavage activity 1, Short name=SCA-1 |
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| Gene, Accession, CAS # | CASP3, Gene ID: 12367, Accession: Q8BNT4 |
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| Catalog # | 1183P-5 |
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| Price | |
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| Order / More Info | Caspase-3 Proform, mouse recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產品資料 |
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