| 產(chǎn)品詳情 |
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| Product Name | Skepinone-L |
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| Description | Skepinone-L is a potent, ATP-competitive inhibitor of p38 MAPK isoform p38α (IC50 = 5 nM) and p38β (97% inhibition at 1 μM). It has little effect on a range of other kinases, including p38γ and p38δ. Skepinone-L dose-dependently blocks the phosphorylation of heat shock protein 27 (HSP27), a p38 MAPK substrate, in response to stimulation with anisomycin (Cat. No. 1549) in HeLa cells (IC50 = 25 nM) or TNF-α in THP-1 cells. MW: 425.4. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[(2,4-difluorophenyl)amino]-7-[(2R)-2,3-dihydroxypropoxy]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-one |
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| Gene, Accession, CAS # | CAS: 1221485-83-1 |
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| Catalog # | B1110-5 |
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| Price | |
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| Order / More Info | Skepinone-L from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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