| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD86 |
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| Clone | IT2.2 |
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| Host Species | Mouse |
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| Reactive Species | human, African green, baboon, capuchin monkey, common marmoset, cotton-topped tamarin, chimpanzee, cynomolgus, rhesus |
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| Isotype | IgG2b, κ |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PE anti-human CD86. CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
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| Immunogen | n/a |
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| Other Names | B7-2, B70 |
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| Gene, Accession # | Gene ID: 942 |
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| Catalog # | 305406 |
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| Price | |
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| Order / More Info | CD86 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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