| 產(chǎn)品詳情 |
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| Antigenic Specificity | Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) |
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| Clone | BNI3 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | unconjugated |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS),Immunocytochemistry (ICC),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)),Immunoprecipitation (IP) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD152 / CTLA-4 is a homodimeric transmembrane protein similar to CD28 and binding the same ligands, i.e. CD80 (B7.1) and CD86 (B7.2), but with higher affinity. Unlike CD28 with important costimulating functions, CD152 acts as an important inhibitory receptor essential for modulation of the immune system. CD152 / CTLA-4 becomes transiently expressed on activated T cells and its malfunction can cause autoimmune diseases, such as insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, or thyroid-associated orbitopathy. |
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| Immunogen | Human CD152-IgG heavy chain fusion protein |
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| Other Names | CTLA-4|CTLA4|CD152|Cd152|Ctla-4|Ly-56|CD|CELIAC3|GRD4|GSE|IDDM12|sCTLA4 |
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| Gene, Accession # | Gene ID: 1493 |
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| Catalog # | ABIN2749015 |
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| Price | |
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| Order / More Info | Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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