| 產(chǎn)品詳情 |
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| Antigenic Specificity | KAP1/TRIM28 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | IHC, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal Picoband? antibody for Transcription intermediary factor 1-beta(TRIM28) detection. Tested with WB, IHC-P in Human;Mouse;Rat. No cross reactivity with other proteins. Tripartite motif-containing 28 (TRIM28), also known as transcriptional intermediary factor 1β (TIF1β) and KAP1 (KRAB-associated protein-1), is a protein that in humans is encoded by the TRIM28 gene. The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. KAP1 is a ubiquitously expressed protein involved in many critical functions including: transcriptional regulation, cellular differentiation and proliferation, DNA damage repair, viral suppression, and apoptosis. Its functionality is dependent upon post-translational modifications. Phosphorylation of KAP1 acts as a deactivator of the protein in many of its mechanisms while sumoylation acts as an activator. |
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| Immunogen | E.coli-derived human KAP1 recombinant protein (Position: A699-P835). Human KAP1 shares 94.9% amino acid (aa) sequence identity with both mouse and rat KAP1. |
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| Other Names | Transcription intermediary factor 1-beta;TIF1-beta;E3 SUMO-protein ligase TRIM28;6.3.2.-;KRAB-associated protein 1;KAP-1;KRAB-interacting protein 1;KRIP-1;Nuclear corepressor KAP-1;RING finger protein 96;Tripartite motif-containing protein 28;TRIM28;KAP1, RNF96, TIF1B; |
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| Gene, Accession # | TRIM28, UniProt: Q13263 |
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| Catalog # | PB9835 |
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| Price | |
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| Order / More Info | KAP1/TRIM28 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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