產(chǎn)品名稱 Altretamine from CAYMAN CHEMICAL COMPANY
產(chǎn)品貨號 23662-50
產(chǎn)品價格 現(xiàn)貨詢價,電話:010-67529703
產(chǎn)品規(guī)格 50 mg
產(chǎn)品品牌 CAYMAN CHEMICAL COMPANY
產(chǎn)品概述
產(chǎn)品詳情
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Product NameAltretamine
DescriptionAn antineoplastic antiproliferative agent; induces toxicity in an ovarian cancer cell line in vitro when used at a concentration of 10 μg/ml, with radiolabeled thymidine uptake equal to 102 and 75% of controls after 48 and 120 hr, respectively; is demethylated in vivo to form bioactive metabolites, which may exert their cytotoxic effect by cross-linking to DNA or generating formaldehyde; reduces colony survival in A204 cells in an NADP-dependent manner in the presence of an S-9 hepatic activating mixture (88 and 30% colony survival without and with NADP, respectively); inhibits tumor growth in vivo of M5076 reticulum cell sarcoma cells by 70% when used at a dose of 150 mg/kg; acts as a chemosterilant in houseflies; a concentration of 0.05% in fly food prevents hatching and pupation in male and female houseflies
Size50 mg
Concentrationn/a
Applicationsn/a
Other Names2,4,6-Tris(dimethylamino)-1,3,5-triazine|Hexamethylmelamine|HMM|NSC 13875
Gene, Accession, CAS #CAS: 645-05-6
Catalog #23662-50
Price
Order / More InfoAltretamine from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
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