| 產(chǎn)品詳情 |
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| Product Name | Pyruvate Dehydrogenase (PDH) Activity Colorimetric Assay Kit |
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| Description | Pyruvate Dehydrogenase (PDH) (EC 1.2.4.1) has a vital role in carbohydrate metabolism. It forms a well-characterized enzyme complex with dihydrolipoyl transacetylase (E2) and dihydrolipoyl dehydrogenase (E3). PDH converts pyruvate into acetyl-CoA in the presence of NAD and CoA, and links glycolysis to the citric acid cycle. PDH activity is inhibited by high intracellular ratios of ATP/ADP, NADH/NAD or Acetyl-CoA/CoA. In humans, PDH deficiency reduces mitochondrial function and is linked to neurodegenerative diseases. PDH deficiency is X-linked; it results in 2 forms of abnormality: a metabolic form (lactic acidosis) and a neurological form (seizure and/or neuropathological spasm). Recent studies show that PDH is a target of oncogene-induced |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | - Measurement of pyruvate dehydrogenase activity in various tissues/cells- Analysis of cell signaling pathway |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K679-100 |
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| Order / More Info | Pyruvate Dehydrogenase (PDH) Activity Colorimetric Assay Kit from BIOVISION, INC. |
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| Product Specific References | n/a |
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