| 產(chǎn)品詳情 |
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| Product Name | SHP099 |
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| Description | Purity >98%. SHP099 is an orally bioavailable inhibitor of SHP2, a non-receptor protein tyrosine phosphatase (IC50 = 71 nM). It stabilizes SHP2 in an auto-inhibited conformation. SHP099 suppresses signaling through the Ras-ERK pathway and blocks the proliferation of receptor tyrosine kinase-driven human cancer cells in vitro and in vivo . |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-(4-amino-4-methyl-1-piperidinyl)-3-(2,3-dichlorophenyl)-2-pyrazinamine |
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| Gene, Accession, CAS # | CAS: 1801747-42-1 |
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| Catalog # | LS-H9916 |
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| Price | |
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| Order / More Info | SHP099 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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