| 產(chǎn)品詳情 |
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| Product Name | CD44 (CD44) (C-Term), (AA 21-220) protein |
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| Description | Recombinant Human CD44 is produced by our mammalian expression system. The target protein is expressed with sequence (Gln21-Pro220) of Human CD44 fused with a FC tag at the C-terminus. CD44 is a cell-surface receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. A large number of CD44 isoforms can be generated by the insertion of different combinations of at least nine exons. Increased CD44 antigen is associated with relapses in non-small cell lung cancers. Furthermore, an increasing quantity of evidence suggests that CD44 has various functions related to inflammatory disease. CD44 deficiency induces severe liver injury. CD44-hyaluronate mediates in lymphocyte T and monocyte adhesion to the endothelium, stimulates proinflammatory cytokine release from macrophages and participates in dedifferentiation phenotype of smooth muscle cells from contractile state to synthetic one. |
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| Size | 50 μg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AU023126|AW121933|AW146109|HERMES|Ly-24|Pgp-1|CD44A|METAA|RHAMM|CDW44|CSPG8|ECMR-III|HCELL|HUTCH-I|IN|LHR|MC56|MDU2|MDU3|MIC4|Pgp1 |
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| Gene, Accession, CAS # | Gene ID: 960 |
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| Catalog # | ABIN1691534 |
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| Order / More Info | CD44 (CD44) (C-Term), (AA 21-220) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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