| 產品詳情 |
| Edit |   |
|---|
| Product Name | BVT 948 |
|---|
| Description | A cell-permeable inhibitor of PTPs (IC50s = 0.09-1.7 μM) through oxidation of the catalytic cysteine residue; inhibits redox-sensitive CYP isoforms with IC50 values less than 10 μM; inhibits the protein methyltransferases SETD8, SETD2, G9a, SMYD2, CARM1, and PRMT3 with IC50 values from 0.7 to 3.2 μm |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | biochemical inhibitor cytochrome P450 phosphatase methyltransferase epigenetic histone modification diabetes cancer neuroscience intracellular signaling BVT948 inhibit protein tyrosine phosphatase noncompetitive cell-permeable PTP facilitate oxidation catalytic cysteine residue hydrogen peroxide redox-sensitive CYP450 isoform insulin tolerance ob/ob obese/obese mice mouse suppress expression matrix metalloproteinase-9 MMP-9 MMP9 invasion breast increase NMDA-induced N-Methyl-D-aspartic acid N-Methyl-D-aspartate substance P release spinal cord slice |
|---|
| Gene, Accession, CAS # | CAS: 39674-97-0 |
|---|
| Catalog # | 16615-10 |
|---|
| Price | |
|---|
| Order / More Info | BVT 948 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 產品資料 |
|
|