| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | AUDA |
|---|
| Description | AUDA is an inhibitor of sEH exhibiting IC50 values of 18 and 69 nM for the mouse and human enzymes, respectively.{14064} In angiotensin-infused rats, a dose of 25 mg/l AUDA administered in drinking water decreased mean arterial blood pressure from 161 ± 4 mmHg to 140 ± 5 mmHg. This hypotensive effect was accompanied by an increase in urinary epoxide-to-diol ratios.{14065} AUDA activates PPARα 3-fold at a concentration of 10 μM but exhibits no affect on PPAR.delta. or PPARγ.{13447} |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | epoxides hydrolases hypertension dihydroxy-eicosatrienoic acids DHETs 11(12)-EETs 14(15)-EETs blood pressure soluble sEH inhibits inhibitors inhibition peroxisome proliferator-activated receptors PPARalpha PPAR.alpha. DiHETrEs EpETrEs endocrinology |
|---|
| Gene, Accession, CAS # | CAS: 479413-70-2 |
|---|
| Catalog # | 10007927-10 |
|---|
| Price | |
|---|
| Order / More Info | AUDA from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|