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| Antigenic Specificity | TIA-1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TIA-1 Polyclonal Antibody. The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. |
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| Immunogen | n/a |
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| Other Names | TIA1; TIA1 cytotoxic granule-associated RNA binding protein ; TIA1 cytotoxic granule-associated RNA-binding protein; TIA1 protein; cytotoxic granule-associated RNA-binding protein; p40-TIA-1 (containing p15-TIA-1) |
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| Gene, Accession # | Entrez: 21841, 7072; Uniprot: P31483, P52912 |
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| Catalog # | A303-990A |
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| Price | |
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| Order / More Info | TIA-1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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