| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD54 |
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| Clone | HCD54 |
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| Host Species | Mouse |
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| Reactive Species | human, cross-reactivity: chimpanzee |
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| Isotype | IgG1, κ |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), Immunofluorescence Microscopy (IF) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human CD54. CD54 is a 85-110 kD type I transmembrane protein also known as ICAM-1. It is expressed on activated endothelial cells, high endothelial venules, T and B cells, monocytes/macrophages, granulocytes, and dendritic cells. The expression of ICAM-1 on the cell surface is potently upregulated by activation; a soluble form of ICAM-1 can be released from the cell surface. CD54 plays a role in cellular adhesion and is involved in inflammation and leukocyte extravasation. CD54 has also been shown to be the major cellular receptor for rhinovirus. ICAM-1 binds to CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150, 95) as well as hyaluronan and fibrinogen. |
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| Immunogen | n/a |
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| Other Names | ICAM-1, ICAM1 |
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| Gene, Accession # | Gene ID: 3383 |
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| Catalog # | 322702 |
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| Price | |
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| Order / More Info | CD54 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 19325128 |
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| 產(chǎn)品資料 |
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