| 產(chǎn)品詳情 |
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| Antigenic Specificity | TCCR |
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| Clone | 263517 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2A |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | lyophilized |
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| Applications | Western Blot: 1 μg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TCCR Monoclonal Antibody (263517). Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominately expressed in thymus, sple |
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| Immunogen | n/a |
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| Other Names | UNQ296/PRO336, CRL1, IL27R, TCCR, WSX1, zcytor1, IL-27 receptor subunit alpha, IL-27R subunit alpha, IL-27R-alpha, IL-27RA, T-cell cytokine receptor type 1, class I cytokine receptor, cytokine receptor-like 1, interleukin-27 receptor subunit alpha, type I T-cell cytokine receptor |
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| Gene, Accession # | Entrez: 50931; Uniprot: O70394 |
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| Catalog # | MA5-23966 |
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| Price | |
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| Order / More Info | TCCR Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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