| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | MBD3 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 μL |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot: 1:500-1:3000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | MBD3 Polyclonal Antibody. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain. However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71% and 94% identity with MBD2 and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. |
|---|
| Immunogen | n/a |
|---|
| Other Names | methyl-CpG-binding domain protein 3, CpGbinding domain protein 3, CpGbinding domain 3 |
|---|
| Gene, Accession # | Entrez: 53615; Uniprot: O95983 |
|---|
| Catalog # | PA5-34851 |
|---|
| Price | |
|---|
| Order / More Info | MBD3 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|