| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | Recombinant Mouse Transcription factor GATA-4 (GATA4) |
|---|
| Description | Purity > 85% as determined by SDS-PAGE. MW: 49.6kDa. Full Length: 1-441aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Mus musculus (Mouse). Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development. May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | GATA-binding factor 4; Gata-4 |
|---|
| Gene, Accession, CAS # | GATA4, UniProt: Q08369 |
|---|
| Catalog # | RPC21355 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Mouse Transcription factor GATA-4 (GATA4) from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|