| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | PX 12 |
|---|
| Description | Thioredoxin-1 (Trx-1) inhibitor; irreversibly inactivates Trx-1 as a substrate for reduction by thioredoxin reductase (TR); competitively inhibits the reduction of Trx-1 by TR (Ki = 30.8 μM). Attenuates expression of HIF-1α, VEGF and iNOS (IC50 values are 7.2, 10.4 and 18.1 μM respectively). Exhibits antitumor activity; directly inhibits tubulin in vitro and decreases tumor microvessel density in vivo. Purity 99%. MW (observed): 188.31 |
|---|
| Size | 50 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 2-[(1-Methylpropyl)dithio]-1H-imidazole. IV-2 |
|---|
| Gene, Accession, CAS # | CAS: 141400-58-0 |
|---|
| Catalog # | 2954/50 |
|---|
| Price | |
|---|
| Order / More Info | PX 12 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 22463935, 24260080 |
|---|
| 產(chǎn)品資料 |
|
|