| 產(chǎn)品詳情 |
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| Product Name | BRAF, 432-766aa, Human, His tag, E.coli (Denatured) |
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| Description | Purity: > 80% by SDS - PAGE Format: Liquid, In 20mM Tris-HCl (pH8.0) containing 10% glycerol. BRAF belongs to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. Recombinant human BRAF protein, fused to His-tag at N-terminus, was expressed in E.coli. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Serine/threonine-protein kinase B-raf, Serine/threonine-protein kinase B-raf, B-RAF1, BRAF1, NS7, RAFB1 |
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| Gene, Accession, CAS # | NP 004324 |
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| Catalog # | ATGP2924 |
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| Order / More Info | BRAF, 432-766aa, Human, His tag, E.coli (Denatured) from ATGen |
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| Product Specific References | n/a |
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