| 產(chǎn)品詳情 |
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| Product Name | Tubastatin A |
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| Description | Cell-permeable. A potent and selective HDAC6 (histone deacetylase 6) inhibitor. Displays 1093-fold selectivity over HDAC1 (IC50 values of 15 nM for HDAC6 vs 16.4 μM for HDAC1). Tubastatin A was substantially more selective than the known HDAC6 inhibitor Tubacin at all isozymes except HDAC8. In addition, it displayed over 1000-fold selectivity against all HDAC isoforms excluding HDAC8, where it displayed 54-fold selectivity. Tubastatin A displayed dose-dependent protection against HCA (homocysteic acid)-induced neuronal cell death starting at 5 μM with near complete protection at 10 μM. MW: 371.86. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n-Hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]-indol-5(2H)-yl)methyl)benzamide |
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| Gene, Accession, CAS # | CAS: 1239262-52-2 |
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| Catalog # | 1724-5 |
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| Price | |
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| Order / More Info | Tubastatin A from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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