| 產品詳情 |
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| Antigenic Specificity | AKT1 |
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| Clone | RM252 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | Protein A purified |
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| Size | 50 μl |
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| Concentration | n/a |
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| Applications | IHC, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit monoclonal antibody to detect Akt1 in human samples. The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 and Akt 3, which exhibit sequence homology with the protein kinase A and C families and are encoded by the c-Akt proto-oncogene. They have a pleckstrin homology domain. Akt1 and Akt2 are activated by PDGF stimulation. This activation is dependent on PDGFR-? tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1(IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Phosphorylation of both residues is important to generate a high level of Akt1 ac |
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| Immunogen | A synthetic peptide corresponding to the C-terminus of human Akt1 |
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| Other Names | PKB, RAC, Protein kinase B, Protein kinase B alpha, Short PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha, RAC-alpha serine/threonine-protein kinase |
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| Gene, Accession # | Gene ID: 207, Accession: P31749 |
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| Catalog # | A1117-50 |
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| Price | |
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| Order / More Info | AKT1 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產品資料 |
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