| 產(chǎn)品詳情 |
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| Product Name | PFK158 |
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| Description | A PFKFB3 inhibitor (IC50 = 137 nM for human recombinant PFKFB3); inhibits PFKFB3 and glycolysis in Jurkat cells (IC50s = 1.6 and 0.847 μM, respectively); inhibits the growth of leukemia cells in vitro (IC50 = 0.33 μM for Jurkat cells); reduces tumor volume in CT-26 murine colon carcinoma syngeneic model and a BxPC-3 pancreatic cancer mouse xenograft model; enhances activity of the anti-CTLA-4 antibody in the B16/F10 mouse model of melanoma |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PFK-158 CT26 BxPC3 CTLA4 PFKFB-3 B-16 F-10 |
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| Gene, Accession, CAS # | CAS: 1462249-75-7 |
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| Catalog # | 22987-5 |
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| Price | |
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| Order / More Info | PFK158 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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