| 產(chǎn)品詳情 |
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| Product Name | Human CellExp? PCSK9, murine recombinant |
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| Description | Proprotein convertase subtilisin/kexin type 9 (PCSK9), is an enzyme which in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A (EGF-A) domain of the low-density lipoprotein receptor (LDLR), inducing LDLR degradation. PCSK9 may also have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a rare form of autosomal dominant familial hypercholesterolemia (HCHOLA3). This protein is fused with 6xHis tag at the N-terminus, has a calculated MW of 72 kDa. The predicted N-ter |
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| Size | 20 μg |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | PCSK9, FH3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9, Proprotein convertase subtilisin/kexin type 9 |
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| Gene, Accession, CAS # | PCSK9, Gene ID: 100102, Accession: Q80W65 |
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| Catalog # | 7266-20 |
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| Price | |
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| Order / More Info | Human CellExp™ PCSK9, murine recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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