| 產(chǎn)品詳情 |
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| Antigenic Specificity | NPM |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 μg |
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| Concentration | 0.5 mg/ml |
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| Applications | Western blot, Immunohistochemistry |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NPM Antibody. NPM (Nucleophosmin) is an abundant phosphoprotein primarily found in nucleoli. It has been implicated in several distinct cellular functions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication and molecular chaperoning activities. The NPM gene is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. The NPM portion contributes to transformation by providing a dimerization domain, which results in activation of the fused kinase. |
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| Immunogen | Synthetic peptide corresponding to amino acids surrounding the N-terminus of human NPM |
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| Other Names | B23 , numatrin , NO38 , MGC104254 , Nucleophosmin , NPM1, Nucleolar phosphoprotein B23; Nucleolar protein NO38 |
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| Gene, Accession # | Gene ID: 114762, Accession: P06748 |
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| Catalog # | 3425-100 |
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| Price | |
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| Order / More Info | NPM Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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