| 產(chǎn)品詳情 |
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| Product Name | Huwentoxin IV |
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| Description | Selective NaV1.7 channel blocker. Preferentially inhibits neuronal NaV1.7, 1.2 and 1.3 (IC50 values are 26, 150 and 338 nM respectively), compared to muscle subtypes NaV1.4 and 1.5 (IC50 = >10 μM). Inhibits the channel by binding at the neurotoxin receptor site 4 in the S3-S4 linker of domain II, trapping the voltage sensor in the inward, closed configuration. MW (observed): 4106.79. |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CAS: 526224-73-7 |
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| Catalog # | 4718/100U |
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| Price | |
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| Order / More Info | Huwentoxin IV from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 30765606 |
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| 產(chǎn)品資料 |
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