| 產(chǎn)品詳情 |
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| Antigenic Specificity | Complement C5a |
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| Clone | 2952 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | ELISA: 1:50, Functional Assay: 1:50, Immunohistochemistry (Frozen): 1:50, Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:50 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Complement C5a Monoclonal Antibody (2952). Monoclonal antibody 2952 reacts with a neo-epitope on C5a (des-Arg) that is formed upon cleavage of C5 into C5a and C5b. C5 is involved in the activation of the lythic pathway within the complement system which is an important factor in innate immunity. The complement pathways can be divided in the activation pathways and lytic pathway. The activation pathways lead via C3 to the cleavage of the fifth complement component C5. C5a induces smooth muscle contraction, increases vascular permeability, causes degranulation of mast cells and basophils, and release of lysosomal enzymes. In addition C5a stimulates the directed migration of neutrophils, eosinophils, basophils and monocytes. Recent studies ind |
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| Immunogen | n/a |
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| Other Names | CPAMD4, FLJ17816, FLJ17822, MGC142298 |
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| Gene, Accession # | Entrez: 727; Uniprot: P01031 |
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| Catalog # | MA1-40162 |
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| Price | |
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| Order / More Info | Complement C5a Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 26673143 |
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| 產(chǎn)品資料 |
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