| 產(chǎn)品詳情 |
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| Product Name | PRKAB2, 1-272aa, Human, His tag, E.coli (Denatured) |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 2M urea . PRKAB2 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. PRKAB2 may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Recombinant human PRKAB2 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | 5'-AMP-activated protein kinase subunit beta-2 |
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| Gene, Accession, CAS # | NP 005390 |
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| Catalog # | ATGP1817 |
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| Price | |
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| Order / More Info | PRKAB2, 1-272aa, Human, His tag, E.coli (Denatured) from ATGen |
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| Product Specific References | n/a |
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