| 產(chǎn)品詳情 |
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| Product Name | PPARγ Ligand Screening/Characterization Assay Kit (Fluorometric) |
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| Description | The Peroxisome Proliferator Activated Receptor (PPAR) family of ligand-activated transcription factors consists of three subtypes encoded by separate genes: PPARα, PPARδ and PPARγ. Of these, PPARγ plays an important role in the regulation of fatty acid storage and glucose metabolism. The genes activated by PPARγ stimulate lipid uptake and adipogenesis by fat cells. Many endogenous molecules such as, polyunsaturated fatty acids like arachidonic acid and its metabolites, are known to bind and activate PPARγ. The binding of activating ligands to the ligand binding domain (LBD) of PPARγ promotes its heterodimerization with retinoic acid-like receptor (RXR), which results in the regulated expression of t |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | ? Rapid, high-throughput screening of drugs and novel ligands. ? Development of structure-activity relationship (SAR) models to predict PPARγ/ligand interaction liability of novel compounds. |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K437-100 |
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| Order / More Info | PPARγ Ligand Screening/Characterization Assay Kit (Fluorometric) from BIOVISION, INC. |
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| Product Specific References | n/a |
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