產(chǎn)品名稱 PF-06463922 from BIOVISION, INC.
產(chǎn)品貨號 B1169-50
產(chǎn)品價格 現(xiàn)貨詢價，電話：010-67529703
產(chǎn)品規(guī)格 50 mg
產(chǎn)品品牌 BIOVISION, INC.
產(chǎn)品概述
產(chǎn)品詳情
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Product NamePF-06463922
DescriptionPF-06463922 is a potent, selective, brain-penetrant, and high affinity ALK (Anaplastic lymphoma kinase) and ROS1 (c-Ros oncogene 1) inhibitor displaying >100-fold selectivity for ROS1 over panel of 204 other kinases. It has strong activity against all known ALK and ROS1 mutants identified in patients, including the EML4-L1196M mutant of ALK (Ki = < 0.02 nM). It inhibits proliferation of BaF3 cells containing Crizotinib resistant ROS1 mutation in vitro. MW: 406.41. Purity ≥98% by HPLC
Size50 mg
Concentrationn/a
Applicationsn/a
Other Names(10R)-7-Amino-12-fluoro-10,15,16,17-tetrahydro-2,10,16-trimethyl-15-oxo-2H-4,8-methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile
Gene, Accession, CAS #CAS: 1454846-35-5
Catalog #B1169-50
Price
Order / More InfoPF-06463922 from BIOVISION, INC.
Product Specific Referencesn/a
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