| 產(chǎn)品詳情 |
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| Product Name | PF 05212384 |
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| Description | Purity ~98% (HPLC). Potent and selective dual inhibitor of PI 3-kinase/mTOR (IC50 values are 0.4, 1.6 and 5.4nm for PI 3-Kalpha, mTOR and PI 3-Kgamma respectively). Exhibits selectivity over 234 other protein kinases (IC50 >10um). Potently inhibits tumor cell growth in 37 different tumor cell lines (IC50 < 100nm). Also exhibits antitumor activity in MDA-361, HCT-116, H1975 and U87MG xenograft models. Sequence: C32H41N9O4 Solubility: DMSO (~5mM) with gentle warming Molecular Weight: ~615.73 |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PF 05212384 (PKI-587) (N-[4-[[4-(Dimethylamino)-1-piperidi nyl]carbonyl]phenyl]-N'-[4-(4,6-di-4-morpholinyl-1, 3,5-triazin-2-yl)phenyl]urea) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 145689 |
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| Price | |
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| Order / More Info | PF 05212384 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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