| 產(chǎn)品詳情 |
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| Antigenic Specificity | mTOR |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 μl |
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| Concentration | n/a |
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| Applications | Western blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | mTOR Antibody. The mammalian target of rapamycin (mTOR, FRAP, RAFT) is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to balance nutrient availability and cell growth. When sufficient nutrients are available, mTOR responds to a phosphatidic acid-mediated signal to transmit a positive signal to p70 S6 kinase and participate in the inactivation of the eIF4E inhibitor, 4E-BP1. These events result in the translation of specific mRNA subpopulations. mTOR is phosphorylated at Ser2448 via the PI3 kinase/Akt signaling pathway and autophosphorylated at Ser2481. mTOR plays a key role in cell growth and homeostasis and may be abnormally regulated in tumors. For these reasons, mTOR is currently under investigation as a potentia |
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| Immunogen | Synthetic peptide of human mTOR |
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| Other Names | FRAP1, FK506 binding protein 12-rapamycin associated protein 1; FRAP2, FK506 binding protein 12-rapamycin associated protein 2; RAFT1, RAPT1 |
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| Gene, Accession # | Gene ID: 2475, Accession: NP_004949.1 |
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| Catalog # | 3786-100 |
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| Price | |
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| Order / More Info | mTOR Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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