| 產(chǎn)品詳情 |
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| Antigenic Specificity | BMPR2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse. |
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| Isotype | n/a |
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| Format | saturated ammonium sulfate precipitate |
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| Size | 100 μl |
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| Concentration | n/a |
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| Applications | Western blot, IHC, FACS. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Polyclonal Antibody to detect BMPR2 in human and mouse samples. BMPR2 is a type II serine/threonine receptor kinase that binds to an array of secreted bone morphogenetic proteins (BMPs). BMPs belong to the superfamily of TGF-β ligands that modulate gastrulation, neurogenesis, chondrogenesis, interdigital cell death, and bone morphogenesis. In contrast to the TGF-β type II receptor, BMPR2 contains an extended carboxyl-terminal region that interacts with multiple signaling molecules to modulate the responsiveness of target genes to BMPs. BMP signaling requires oligomerization of both type I and type II receptors to elicit a functional response of target genes. BMP binding to type I and II receptors induces Smad1/5/8 phosphorylation |
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| Immunogen | This BMPR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-59 amino acids from the N-terminal region of human BMPR2. |
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| Other Names | BMPR2; PPH1; Bone morphogenetic protein receptor type-2; Bone morphogenetic protein receptor type II |
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| Gene, Accession # | Gene ID: 659, Accession: Q13873 |
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| Catalog # | 6780-100 |
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| Price | |
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| Order / More Info | BMPR2 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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