| 產(chǎn)品詳情 |
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| Product Name | Halofuginone (hydrochloride) |
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| Description | A halogenated derivative of febrifugine that down-regulates Smad3, blocking TGF-β signaling relevant to fibrosis and tumor progression in a variety of different models; competitively inhibits prolyl-tRNA synthetase (Ki = 18.3 nM), preventing the differentiation of TH17 cells and blunting an autoimmune response |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 55837-20-2 inhibitors inhibitions inhibits cancers genes regulations autoimmunity infectious diseases immunology HCl TGF-β TGF-.beta. TGF-beta TGF-b TGF β .beta. beta b signals signaling TH17 differentiation derivatives febrifugine D. D febrifuga antimalarial anti-malarial anti malarial malaria anticoccidial anti-coccidial coccidial Smad3 fibroblasts myofibroblasts epithelial cells mesenchymal fibrosis tumors competitive competitively prolyl-tRNA prolyl tRNA synthetase monohydrochloride autoimmune diseases |
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| Gene, Accession, CAS # | CAS: 1217623-74-9 |
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| Catalog # | 13370-1 |
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| Price | |
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| Order / More Info | Halofuginone (hydrochloride) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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