| 產(chǎn)品詳情 |
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| Antigenic Specificity | Human BNIP3L |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC-P |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human BNIP3L polyclonal antibody for IHC-P. Members in the BCL-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. BCL-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including BAD, BAX, BID, BIK, HRK, NIP3, and BIM, form a growing subclass of the BCL-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3, and NIX (for NIP3-like protein X) . Bnip3L/Bnip3/Nix is a homolog of the E1B 19K/BCL-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis. Bnip3L interacts with and overcomes suppression by BCL-2 and BCL-XL. Bnip3L is localized in mitochondria. The messenger RNA of Bnip3L is ubiquitously expressed in human tissues. Bnip3L and Bnip3 form a new subfamily of the pro-apoptotic mitochondrial proteins. |
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| Immunogen | Synthetic peptide |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 665, UniProt: O60238 |
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| Catalog # | CABT-L1703 |
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| Price | |
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| Order / More Info | Human BNIP3L Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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