| 產(chǎn)品詳情 |
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| Antigenic Specificity | Human BAF53A |
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| Clone | 6I4M7 |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | FC, ICC, IF, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human BAF53A monoclonal antibody for FC, ICC, IF, WB. BAF53A is a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. |
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| Immunogen | Peptide corresponding to human BAF53A (aa124-142) |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 86, UniProt: O96019 |
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| Catalog # | CABT-L1180 |
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| Price | |
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| Order / More Info | Human BAF53A Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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