| 產(chǎn)品詳情 |
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| Antigenic Specificity | Human ATG4B |
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| Clone | 2ID7MD20 |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, nonhuman primate |
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| Isotype | IgG |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | FC, ICC, IHC-P, IF, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human ATG4B monoclonal antibody for FC, ICC, IHC-P, IF, WB. Cysteine protease ATG4b is an enzyme which is coded by ATG4b gene. Autophagy is a critical cellular homeostatic process that controls the turnover of damaged organelles and protein. ATG4b is a deubiquitin-like protease that plays dual roles in the core machinery of autophagy. ATG4b, cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. ATG4b is mainly expressed in the skeletal muscle, brain, heart, liver and pancreas. |
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| Immunogen | Full-length protein corresponding to human ATG4B |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 23192, UniProt: Q9Y4P1 |
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| Catalog # | CABT-L1203 |
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| Price | |
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| Order / More Info | Human ATG4B Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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