| 產(chǎn)品詳情 |
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| Antigenic Specificity | Human APP (N-terminal, aa 1-14) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ELISA, IHC, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human APP (N-terminal) polyclonal antibody for ELISA, IHC, WB. Amyloid β (Aβ) is the peptide that accumulates in the brain in Alzheimer`s disease and certain classes of cerebrovascular angiopathy. Alzheimer`s disease (AD) is characterized by the progressive formation in the brain of insoluble amyloid plaques and vascular deposits consisting of the 4-kD Aβ-peptide. Aβ generation is initiated by proteolytic cleavage of the amyloid precursor protein (APP) at the N-terminal of Aβ by β-secretase. The Aβ peptide is then released by proteolytic cleavage at its C-terminus by g-secretase. The insoluble Aβ peptide forms aggregates in the vessels and senile plaques of AD brains. |
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| Immunogen | Peptide (DAEFRHDSGYEVHH) |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 351, UniProt: P05067 |
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| Catalog # | CABT-L521 |
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| Price | |
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| Order / More Info | Human APP (N-terminal, aa 1-14) Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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