| 產(chǎn)品詳情 |
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| Antigenic Specificity | CD8a |
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| Clone | 5H10-1 |
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| Host Species | Rat (SD) |
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| Reactive Species | mouse |
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| Isotype | IgG2b, λ |
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| Format | purified |
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| Size | 50 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), Immunofluorescence Microscopy (IF), IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-mouse CD8a. CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. |
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| Immunogen | Concanavalin A-stimulated BALB/c splenic T cells |
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| Other Names | T8, Ly-2, Lyt-2 |
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| Gene, Accession # | Gene ID: 12525 |
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| Catalog # | 100801 |
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| Price | |
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| Order / More Info | CD8a Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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