| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Product Name | Acid Sphingomyelinase Activity Colorimetric Assay Kit |
|---|
| Description | Sphingomyelinase (SMase) cleaves sphingomyelin to produce phosphorylcholine and ceramide. The activation of SMase leads to increased production of ceramide, which acts as a lipid second messenger. There are five distinct types of SMases. Deficiency in Acid SMase (ASMase) leads to Niemann-Pick disease type A and B. BioVision's Acid Sphingomyleinase Activity Assay Kit provides a simple and sensitive method for measuring ASMase enzymatic activity using colorimetry (OD 570 nm). In this assay, ASMase converts its substrate, sphingomyelin to phosphorylcholine and ceramide at pH 5.0; subsequently, phosphorylcholine is utilized in a series of reactions culminating in color formation from a highly specific probe. This high-throughput adaptable assay |
|---|
| Size | 100 assays |
|---|
| Concentration | n/a |
|---|
| Applications | ? Measurement of ASMase activity in various tissues/cell extracts? Screening of ASMase inhibitors |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | K598-100 |
|---|
| Price | |
|---|
| Order / More Info | Acid Sphingomyelinase Activity Colorimetric Assay Kit from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
|