| 產(chǎn)品詳情 |
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| Antigenic Specificity | ACKR3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat, monkey |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | WB, IHC, ELISA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Polyclonal Antibody against AGTR5. Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby |
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| Immunogen | Synthesized peptide derived from the C-terminal region of human CXCR-7 (290-370aa) |
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| Other Names | ACKR3; CXCR7; CMKOR1; GPR159; RDC1; C-X-C chemokine receptor type 7; CXC-R7; CXCR-7; Chemokine orphan receptor 1; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog; RDC-1 |
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| Gene, Accession # | Gene ID: 57007, Accession: P25106 |
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| Catalog # | A1066-100 |
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| Price | |
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| Order / More Info | ACKR3 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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