| 產(chǎn)品詳情 |
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| Antigenic Specificity | PAR-2 |
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| Clone | SAM11 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 μl |
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| Concentration | n/a |
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| Applications | IHC-P, Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-PAR-2. Proteinase-activated receptor 2 (PAR-2), also known as G-protein coupled receptor 1 or thrombin receptor-like 1, is a receptor for trypsin and trypsin-like enzymes coupled to G proteins. The function of PAR-2 is mediated through the activation of multiple signaling pathways, including MAPK, phospholipase C, intracellular calcium, and I-kappaB kinase/NF-kappaB and Rho. PAR-2 is involved in the regulation of innate and adaptive immunity, the modulation of inflammatory responses, and as a sensor of proteolytic enzymes generated during the course of infection. PAR-2 is also involved in the recruitment of leukocytes to inflammation sites, promotion of dendritic cell maturation and trafficking to lymph nodes, production of superoxide, and T-cell activation. |
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| Immunogen | This monoclonal antibody was raised against human PAR-2 protein and was mapped to amino acids 37-50. |
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| Other Names | Proteinase-activated receptor 2, thrombin receptor-like 1, G-protein coupled receptor 11, protease-activated receptor 2, coagulation factor II receptor-like 1, MMS-5116-100 |
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| Gene, Accession # | Gene ID: 2150 |
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| Catalog # | 817201 |
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| Price | |
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| Order / More Info | PAR-2 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 產(chǎn)品資料 |
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